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№3' 2014

OBSTETRICS AND GYNECOLOGY

International Medical Journal, Vol. 20., Iss. 3, 2014, P. 87−91.

Clinical hormonal characteristics and therapy of girls with endometrial hyperplasia and anemia

Kharkiv National Medical University, Ukraine

Genital pathology manifested by hemorrhagic syndrome in children and adolescents is the most common and difficult problem of contemporary gynecology. This group of patients includes those with puberty uterine bleeding which often have secondary post−hemorrhagic anemia significantly reducing their quality of life and requiring timely adequate therapy. The aim of the study was to improve the diagnosis of puberty uterine bleeding against a background of anemia for further selection and application of complex conservative therapy. The study involved 128 girls aged 11−18 with puberty uterine bleeding. The complex investigation included clinical, gynecological examination, ultrasound, analysis of pathomorphologic picture of endometrium, hormonal profile. The study demonstrated that 75 % of girls had extragenital pathology, 76.5 % secondary iron deficiency anemia, 79.7 % hormonal disorders. Histological examination of the endometrium and ultrasound data established the presence of endometrial hyperplasia in 62.3 % of patients. Conservative therapy of puberty uterine bleeding included a complex dietary supplement Indol−F®, which resulted in acceleration of hemostasis, high efficiency of treatment of endometrial hyperplasia and reduction of recurrence of puberty uterine bleeding in patients as well as reduced the treatment time and was not accompanied by side effects and complications.

Key words: adolescent girls, puberty uterine bleeding, endometrial hyperplasia, Indol−F®.