Previous
Next
ARCHIVE
№4' 2016
ANDROLOGYInternational Medical Journal, Vol. 22., Iss. 4, 2016, P. 42−45.
ASSESSING THE LEVEL OF SEX HORMONES AND LIPID PROFILE IN MEN WITH INFERTILITY AT METABOLIC SYNDROME AND HIGH BODY MASS INDEX
Kharkiv Medical Academy of Postgraduate Education
V. I. Gryshchenko Clinic of Reproductive Medicine
Treatment of men with pathospermia against a background of metabolic syndrome (MS) depends on the body mass index (BMI), severity of the common manifestations of MS, its duration, disorders of sexual function. The existing schemes of therapeutic recovery of androgen function in men with metabolic syndrome are ineffective in the majority of cases, thus justifying the search for new methods of treatment for pathospermia. Analysis of treatment for pathospermia in men with metabolic syndrome with the drugs that improve and stimulate testicular blood circulation was performed. Besides the lifestyle correction, administration of vasoactive drugs and statins, human chorionic gonadotropin was added to the treatment protocol. The treatment quality was assessed by comparison of baseline levels of hormones and lipid profile before and 12 weeks after the prescribed therapy. The hormone levels before and after treatment (combination of cardiovascular drugs, statin, human chorionic gonadotropin), normalization of lipid metabolism, adherence to strict guidelines on the weight loss, correction of the lifestyle demonstrated the prospects of the method of pathogenetic treatment for pathospermia in men with MS and increased BMI. The increase in total testosterone in patients with hypogonadism is an additional advantage of this type of therapy.
Key words: pathospermia, metabolic syndrome, testosterone.