International Medical Journal, Vol. 23., Iss. 1, 2017, P. 21−24.
FUNCTIONAL MYOCARDIUM ASSESSMENT IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND HYPERTENSIVE DISEASE
Kharkiv National Medical University, Ukraine
Hypertensive disease and chronic obstructive pulmonary disease are common around the world; they are characterized by chronic progressive course and require lifelong treatment. Development of chronic heart failure as a result of cardiovascular diseases and complicated COPD is a well−known phenomenon. To study the question of the ways of development of chronic heart failure in the presence of the pathology of the cardiovascular and respiratory systems we estimated systolic and diastolic function of the heart chambers in patients with COPD and hypertonic disease. Left ventricle diastolic and systolic diameters, posterior wall thickness, interventricular septum, left ventricular ejection fraction were measured at ultrasound examination. LV myocardium mass was calculated by Devereux R. et al. Diastolic function of the both ventricles was assessed using pulsed Doppler study and fractional area change. The findings showed that the comorbidity was characterized by moderately severe systolic dysfunction in the left ventricle, right ventricular hypertrophy. The study of velocity values of the both ventricles revealed type I of diastolic dysfunction. The patients with concomitant hypertension disease had more pronounced changes in the myocardium, mainly the left portion. The mechanisms underlying myocardial restructuring, require further study. Identification of precipitating factors and factors of progression of myocardial dysfunction can be of great interest. Investigation of interventricular relationship in development of heart failure in patients with chronic obstructive pulmonary disease and concomitant hypertension, as well as structural and functional assessment of the myocardium during the comorbid disease will open new perspectives in treatment and prevention of disability in patients with cardio−pulmonary pathology.
Key words: chronic obstructive pulmonary disease, hypertensive disease, systolic dysfunction, diastolic dysfunction.