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№3' 2018
OBSTETRICS AND GYNECOLOGYInternational Medical Journal, Vol. 24., Iss. 3, 2018, P. 37−39.
DIAGNOSTIC CRITERIA FOR POLYCYSTIC OVARY SYNDROME
Kharkiv National Medical University, Ukraine
The process of cyst formation in the ovaries is a common condition that develops in polycystic ovary syndrome (PCOS) and changes the structure and function of the ovarian tissue. The purpose of this study was to determine the diagnostic value of the clinical−hormonal and echographic criteria of PCOS. The study involved 90 patients, of them 65 had PCOS (main group) and 15 were otherwise healthy (controls). Analysis of parameters of complex gynecological and ultrasound examination of 65 patients demonstrated that in 46 cases (70,8 %) uterine size was less than normal (grade 1 and 2 hypoplasia), and in 19 (29,2 %) − within the limits of normal. In women with PCOS, the ovary volume was almost 3 times greater than in healthy individuals (p < 0,01). The presence of a developing dominant follicle in women of the basic group with PCOS was determined only in 8,8 % of cases, in the controls it was 85 %. The thickness of the ovarian capsule in women with PCOS was also significantly increased (p < 0,001). In women with PCOS, in comparison with the controls, there was a significant increase in the level of prolactin, testosterone (p < 0,05), DHEA−C (p < 0,01), LH (p < 0,01), LH / FSH (p < 0,001), estradiol (p < 0,01), and a decrease in progesterone concentration (p < 0,01). There were no significant changes in the thyroid homeostasis (p > 0,05), which indicates that the thyroid gland does not affect PCOS development in women. Diagnostic criteria of PCOS in women of reproductive age are development of primary infertility, menstrual cycle disorder, hirsutism, obesity, hyperandrogenia, increased ovary volume, absence of maturation of dominant follicles, primary and secondary infertility.
Key words: polycystic ovary syndrome, hyperandrogenia, ultrasound examination, pituitary−ovarian−adrenal system.