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№1' 2020


International Medical Journal, Vol. 26., Iss. 1, 2020, P. 88−92.



Hrek I. I., Anton Viktorovych Rohozhyn, Kushnir V. B., Zaikina Yu. O., Maryna Mykolayivna Kochuieva

Kharkiv Medical Academy of Postgraduate Education
V. N. Karazin Kharkiv National University, Ukraine

Interest to the studies of life quality by scientists and practitioners is constantly growing, as this unique approach allows to fundamentally change the traditional view of the problem of the disease and the patient. By investigating the quality of life as an integral index of the patient's condition, it is possible to assess the complex impact of the disease on the patient's life, to compare the effectiveness of various interventions, to predict the disease course. However, the problem of assessing the quality of life in patients with tuberculosis under conditions of alcohol consumption remains poorly understood. To establish the level of quality of life in patients, 102 men with newly diagnosed tuberculosis, with preserved sensitivity to anti−tuberculosis drugs were examined. The AUDIT test was used to assess their alcohol consumption, and the MOS SF−36 questionnaire was used to analyze the quality of life parameters. The study also assessed quality of life parameters and alcohol consumption in groups with varying prevalence of tuberculosis and the presence of mycobacteria or no bacterial excretion. According to the findings, the following conclusions can be drawn: pulmonary tuberculosis leads to a decrease in quality of life with the greatest depression in the group of patients who abuse alcohol; quality of life indices are significantly lower in patients with advanced tuberculosis and bacterial excretion, while the level of alcohol consumption in these groups is significantly higher than in patients with localized forms and lack of bacterial excretion. Interestingly, when interviewing patients, none of them rated their health as "excellent", answering the first question of the SF−36 questionnaire, and 100 % of respondents to question 11 answered "definitely not" to the statement "I expect my health to deteriorate". The obtained research data on the parameters of quality of life in patients with tuberculosis can be used to achieve the highest effectiveness of therapy and targeted psychosocial rehabilitation.

Key words: tuberculosis, alcohol, quality of life, bacterial excretion.


1. Post M. W. Definitions of quality of life: what has happened and how to move on. Top Spinal Cord Inj Rehabil. 2014. № 20 (3). R. 167−180. doi:10.1310/sci2003−167

2. Razvodovskii Yu. E. Alkogol' i tuberkulez −− populyatsionnyi uroven' vzaimosvyazi // Zhurn. GGMU. 2003. № 3. S. 71−73.

3. A prospective study on Quality of Life in Patients with Pulmonary Tuberculosis at a Tertiary Care hospital in Kashmir, Northern India / S. A. Dar, N. N. Shah, Z. A. Wani, D. Nazir // Indian J. of Tuberculosis. 2018. doi: 10.1016/j.ijtb.2018.07.002

4. Onu D. U., Ifeagwazi C. M., Chukwuorji J. C. Does Posttraumatic Growth Buffer the Association Between Death Anxiety and Quality of Life Among People living with HIV/AIDS? // J. of Clin. Psychology in Medical Settings. 2020. doi:10.1007/s10880−020−09708−6

5. Raznatovska O. M., Khudyakov G. V. Assessment of palliative patients with chemoresistance pulmonary tuberculosis life quality in the conditions of specialized hospital at the corrective labour colony // Zaporozhye medical J. 2017. № 19 (3). R. 358−362. doi:10.14739/2310−1210.2017.3.100936

6. Quality of life and its effective factors in tuberculosis patients receiving directly observed treatment short−course (DOTS) / S. Salehitali, K. Noorian, M. Hafizi, A. H. Dehkordi // J. of Clin. Tuberculosis and Other Mycobacterial. Diseases. 2019. № 15. 100093. doi:10.1016/j.jctube.2019.100093

7. Grek І. І. Vzhivannya alkogolyu khvorimi na vpershe dіagnostovanii tuberkul'oz legen' ta iogo vpliv na perebіg zakhvoryuvannya // Sіmeina meditsina. 2018. № 3 (77). C. 49−53.

8. Tuberkul'oz v Ukraїnі. Analіtichno−statistichnii dovіdnik / DU "Tsentr gromads'kogo zdorov'ya Mіnіsterstva okhoroni zdorov'ya Ukraїni", DZ "Tsentr medichnoї statistiki MOZ Ukraїni". K., 2018. 105 s.

9. Alcohol use disorder and tuberculosis treatment: A longitudinal mixed method study / S. Laprawat, K. Peltzer, W. Pansila, C. Tansakul // S. Afr. J. Psychiat. 2017. № 23 (0). a1074. URL: https:// v23.i0.1074

10. Issledovanie kachestva zhizni bol'nykh tuberkulezom legkikh / E. A. Anis'kina, I. I. Makarova, K. A. Strakhov, S. D. Al'−Daud // Meditsinskaya ekologiya. Ekologiya cheloveka. 2012. № 4. S. 58−62.

11. Velikaya O. V., Akulova A. V. Otsenka kachestva zhizni zhenshchin, bol'nykh tuberkulezom legkikh, s ispol'zovaniem ankety SF−36 // Nauchnye vedomosti. 2015. S. 110−115.

12. Motrich І. V. Kharakteristika yakostі zhittya studentіv, khvorikh na vpershe viyavlenii tuberkul'oz legenіv // Ukr. pul'monologіchnii zhurn. 2008. № 2. S. 68−70.

14. AUDIT The Alcohol Use Disorders Identification Test Guidelines for Use in Primary Care // WHO. 2000. URL:

15. Ware J. E., Sherbourne C. D. The MOS 36−Item Short−Form Health Survey. Med. Care. 1992. № 30 (6). R. 473−483. doi:−199206000−00002

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