Previous Next

ARCHIVE

№3' 2020

OTORHINOLARYNGOLOGY

International Medical Journal, Vol. 26., Iss. 3, 2020, P. 53−59.

DOI (https://doi.org/10.37436/2308-5274-2020-3-10)

FEATURES OF CAPILLARY BLOOD FLOW IN PATIENTS WITH PATHOLOGY OF INTRANASAL STRUCTURES AND NASAL BREATHING DISORDERS

Kharkiv National Medical University, Ukraine

The investigation of the vascular microcirculation system is important for diagnosis, assessment of the severity and nature of pathological processes in human body, monitoring the effectiveness of treatment. Monitoring the state of microcirculation in impaired respiratory function of the nose helps to study the subtle mechanisms of regulation of vascular−tissue relations. To do this, there were used the biomicroscopic methods to study capillary blood flow, one of the most relevant and promising is optical capillaroscopy of the nail bed. This method makes it possible to identify at the evidence level the peculiarities of the functioning of the peripheral circulatory system by the state of the capillary system and to evaluate the effectiveness of treatment by the rheological properties of blood in hematological practice. There were examined 145 patients by means of computer capillaroscopy to study the rate of capillary circulation in the patients with pathology of intranasal structures and nasal breathing disorders. All patients underwent a complete clinical examination, routine instrumental examinations, and computer capillaroscopy using a video capillaroscope with a visual magnification of up to 550 times. The obtained images were stored and processed according to a special software. During the characterization of the capillaroscopic picture there were evaluated: pathological tortuosity, change in the caliber of arterioles and venules, disorganization of the capillary network, the number of functioning capillaries. Changes in the speed and nature of capillary blood flow (accelerated, slow, stasis) were observed. The optical capillaroscopy method allows not only to visually assess the condition of microvessels, but also to determine such an important parameter as blood circulation, actually, it can replace the study of laser Doppler. Such data will be important in the diagnosis of respiratory and olfactory disorders and the formation of adequate tactics for their treatment.

Key words: microcirculation, microcirculatory tract, capillary circulation, nasal obstruction, nasal breathing disorders, pathology of intranasal structures, computer capillaroscopy.

REFERENCES

1. Garbuzenko D. V. Morfofunktsional'naya perestroika pechenochnogo sosudistogo rusla v patogeneze portal'noi gipertenzii pri tsirroze pecheni // Terapevticheskii arkhiv. 2014. № 2. S. 90−93.

2. Iong−Vuk Cho, Park Sung−Kho. Izmerenie skorosti krovotoka pul'py v perednikh zubakh verkhnei chelyusti s ispol'zovaniem ul'trazvukovoi dopplerovskoi floumetrii. URL: http://minimax.ru/articles/foreign/bloodflowpulp.html

3. Remizov A. N. Meditsinskaya i biologicheskaya fizika: uchebnik. M.: GEOTAR−Media, 2013. 648 s.

4. Borisenko A. V., Kuvaev A. S., Viderskaya A. V. Otsenka effektivnosti primeneniya preparatov arginina v kompleksnoi terapii generalizovannogo parodontita pri pomoshchi lazernoi dopplerovskoi floumetrii // Suchasna stomatologіya. 2019. № 3. S. 28−31. doi: 10.33295/1992−576X−2019−3−28

5. High−speed video capillaroscopy method for imaging and evaluation of moving red blood cells / I. Gurov, M. Volkov, N. Margaryants, A. Pimenov // Optics and Lasers in Engineering. 2018. Vol. 104. P. 244−251. doi: https://doi.org/10.1016/j.optlaseng.2017.09.003

6. Chernukh A. M., Aleksandrov P. N., Alekseev O. V. Mikrotsirkulyatsiya. M.: Meditsina, 1984. 432 s.

7. Kovalova A. A., Avrunin O. G. Development of the system of non−invasive express diagnostics of microcirculation // Abstracts of X International Scientific and Practical Conference. San Francisco, USA, 2020. P. 343−346.

8. Personifitsirovannyi pokhod v otsenke mikrotsirkulyatornogo rusla u bol'nykh s zabolevaniyami polosti nosa / M. I. Yashchenkoi dr. // Otorinolaringologіya. 2019. 1s (2). S. 109−110.

9. Koval'ova A. A., Avrunіn O. G. Mozhlivostі otsіnki mіkrotsirkulyatsії za dopomogoyu kapіlyaroskopії // Mater. 1−ї Mіzhnar. nauk.−tekh. konf. "Suchasnі problemi іnfokomunіkatsіi, radіoelektronіki ta nanosistem SPІRN−2019". Vіnnitsya: VNTU, 2019. S. 49−50.

10. Possibilities of automated image processing at optical capillaroscopy / Anastasiia Kovalova et al. // Proc. SPIE 11456, Optical Fibers and Their Applications. 2020, Vol. 11456. 114560G https://doi.org/10.1117/12.2569772

11. Otorinolaringologіya / D. І. Zabolotnii, Yu. V. Mіtіn, S. B. Bezshapochnii, Yu. V. Dєєva. K.: VSV "Meditsina", 2019. 471s.

12. Pukhlik S. M., Dєdikova І. V. Khіrurgіchne lіkuvannya stіikoї obstruktsії porozhnini nosa u patsієntіv z alergіchnim rinіtom // Klіnіchna іmunologіya. Alergologіya. Іnfektologіya. 2015. № 2. S. 10−14.

13. Aleksandrov A. N., Chervinskaya A. V., Ostrinskaya T. V. Galoingalyatsionnaya terapiya bol'nykh allergicheskim i vazomotornym rinitom // Vestn. otorinolaringologii. 2008. № 4. S. 74−77.

14. Svatko L. G., Batyrshin R. G., Batyrshin T. R. Znachenie neirovegetativnykh narushenii v klinike i lechenii vazomotornogo rinita // Vestn. otorinolaringologii. 2008. № 6. S. 17−19.

15. Pukhlik S. M. Zatrudnennoe nosovoe dykhanie // Zdorov'ya Ukraїni. 2010. № 1. S. 54−57.

16. Kozlov V. I. Kapillyaroskopiya v klinicheskoi praktike: monograf. M.: Prakticheskaya meditsina, 2015. 232 s.

17. Kuz'michev A. Ya. Printsipy klinicheskoi kapillyaroskopii: monograf. K.: Zdorov'e, 1965. 170 s.

18. Pokrovskii A. V. Klinicheskaya angiologiya. M.: Meditsina, 2004. 1700 c.

19. Method of expression of certain bacterial microflora mucosa olfactory area / O. G. Avrunin et al. // Proc. SPIE 9816, Optical Fibers and Their Applications. 2015. 98161L (December 18, 2015). doi:10.1117/12.2229074.

20. Nosova Ya. V., Avrunin O. G., Faruk Kh. I. Opredelenie mikrokharakteristik vozdushnogo potoka v nosovoi polosti pri dykhanii // Vestn. NTU "KhPI"; seriya: "Novye resheniya v sovremennykh tekhnologiyakh". Khar'kov: NTU "KhPI". 2018. № 16 (1292). S. 122−127. doi:10.20998/2413−4295.2018.16.19.

21. Suchasnі іntelektual'nі tekhnologії funktsіonal'noї medichnoї dіagnostiki: monograf. / O. G. Avrunіn ta іn. Kharkіv: KhNURE, 2018. 236 s. doi: https://doi.org/10.30837/978−966−659−234−0

22. Іnformatsіinі tekhnologії pіdtrimki priinyattya rіshen' pri viznachennі porushen' nosovogo dikhannya: monograf. / O. G. Avrunіn ta іn. Khar'kov: KhNURE, 2018. 125 s. doi: https://doi.org/10.30837/978−966−659−235−7

23. Principles of computer planning inthefunctional nasalsurgery / O. G. Avrunin et al. // Przegląd Elektrotechniczny. 2017. Vol. 93 (3). P. 140−143.

24. Avrunin O. G., Tomashevskii R. S., Faruk Kh. I. Metody i sredstva funktsional'noi diagnostiki vneshnego dykhaniya. Khar'kov: KhNADU, 2015. 208 s.