International Medical Journal, Vol. 20., Iss. 4, 2014, P. 86−88.
THE STATE OF CEREBRAL HEMODYNAMICS AND BRAIN SUBSTANCE ACCORDING TO DUPLEX SCANNING AND MAGNETIC RESONANCE IMAGING IN MIGRAINE PATIENTS
Kharkiv Medical Academy of Postgraduate Education, Ukraine
Migraine is one of the most widely spread form of headache. It high incidence and increase of morbidity among young, employable people, as well as difficulties in diagnosis and therapy determine a huge interest to this problem. Therefore, the problem of implementation of up−to−date methods of diagnosis becomes extremely significant for investigation of this pathology. At present such highly informative methods, as magnetic resonance imaging (MRI) and duplex scanning (DS) are used in diagnosis of various types of migraine. The aim of the present work was to investigate the state of the brain matter and cerebral hemodynamics using MRI and DS in patients with various kinds of migraine paroxysms. 104 patients aged 16−45 (41 men and 63 women), of them 59 patients with migraine without aura (group 1) and 45 patients with migraine with aura (group 2), underwent complex examination. The state of hemodynamics was investigated using of ultrasound device "Ultima" PA (RADMIR, Ukraine) and transcranial Doppler device "Angiodin" (BIOSS, Russia). Brain MRI was carried out using "Magnetom Concerto" (Siemens, Germany) and Signa HDe (General Electric, USA). According to MRI findings, structural changes in the white matter were revealed in 17 patients (28.8 %) of group 1 and 24 patients (53.3 %) of group 2. These changes were characterized by foci, hypertensive on T2WI and mainly isointensive on T1WI with the dimensions varying within 3 mm to 12 mm. Most often, these foci were localized in temporal (38.6 %) and frontal (31.4 %) lobes. The patients with migraine without aura had predominantly vasospastic reactions in medial cerebral arteries. The patients with migraine with aura manifested hypoperfusion and asymmetry of flow rate in medial cerebral and vertebral arteries, as well as increase of peripheral resistance in medial cerebral arteries. The both groups also manifested redundant blood filling of external carotid arteries.
Key words: cerebral hemodynamics, duplex scanning, magnetic resonance imaging, migraine.